Este fenómeno es conocido como efecto Jod-Basedow. El tratamiento con propiltiouracilo en dosis decrecientes consiguió un estado eutiroideo y mejoró la . Efectos de las hormomas tiroideas en el corazón. Visits . por el efecto de Wolff- Chaikoff, además de hipertiroidismo (mediado por el efecto de Jod-Basedow. de hipertiroidismo (mediado por el efecto de Jod-Basedow. En ambos casos, la causa subyacente es por la alta concentración de yodo en este medicamento.

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The Wolff—Chaikoff effect is also part of the mechanism for the use of potassium iodide in nuclear emergencies. The Japanese-Brazilian thyroid study. The risk of CHD mortality and atrial fibrillation but not other outcomes in subclinical hyperthyroidism is higher among patients with very low levels of thyrotropin.

To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. Iodine and thyroid disease. Subclinical thyroid dysfunction and mortality: Retrieved from ” https: The Jod-Basedow effect typically occurs with comparatively small increases in iodine intake, in people who have thyroid abnormalities that cause the gland to function without the control of the pituitary i.

Mico Endocrinogo de la Clica Comfamiliar Risaralda. Cardiac afterload is increased, and chronotropic and inotropic functions are reduced.

Wolff–Chaikoff effect

The Jod-Basedow effect has also been seen as a side effect of administration of the iodine-containing contrast agents, or amiodaronean antiarrhythmic drug. The Jod-Basedow effect does not occur in persons with normal thyroid glands who ingest extra iodine in any form. Thyroid function after hysterosalpingography using an oil-soluble iodinated contrast efecro. Finally, medications such as amiodarone may induce hypothyroidism mediated by the Wolff—Chaikoffas well as hyperthyroidism mediated by the Jod—Basedow effect.


Disfunci tiroidea posexposici a medio de contraste yodado. Both hypothyroidism and hyperthyroidism increase the risk of coronary artery disease, left cardiomyopathy, electrophysiological abnormalities, and all-cause mortality. Continuing navigation will be considered as acceptance of this use. Hernando Vargas-Uricoechea a.

Neuroendocrinology Pediatric endocrinology Psychoneuroendocrinology Reproductive endocrinology and infertility. This page was last edited on 7 Augustat Clinically, basedpw effect can lead to hypothyroidism.

Larry Jameson, Anthony s. Dorland’s Illustrated Medical Dictionary. Universidad Tecnolica de Pereira. However, unlike the Wolff-Chaikoff effectthe Jod-Basedow effect does not occur in persons with normal thyroid glands, as thyroid hormone synthesis and release in normal persons is controlled by pituitary TSH secretion which does not allow basedoww when extra iodine is ingested.

Wolff–Chaikoff effect – Wikipedia

In general, subclinical hypothyroidism increases the risk of coronary heart disease CHD mortality and CHD events, but not of total mortality. On the other hand, when thyrocites have low iodine levels and are exposed to a high iodine concentration, they increase significantly their production of thyroid hormone thus leading to hyperthyroidism, a phenomenon known as Jod-Basedow effect.

Retrieved from ” https: This page was last edited on 10 Augustat Iodide induced hyperthyroidism with computed tomography contrast fluids. Hyperthyroid subjects given iodide may experience a decrease in basal metabolic rate that is comparable to that seen after thyroidectomy. Thyroiditis and iodide mumps following an angioplasty. Se continuar a navegar, consideramos que aceita o seu uso. Previous article Next article.

Risk of iodine-induced thyrotoxicosis after coronary angiography: On the other hand, in a hypothyroid state, thyroid hormone deficiency results in lower heart rate and weakening of myocardial contraction and relaxation, with prolonged systolic and early diastolic times.


Physiology of the endocrine system.

Jod-Basedow phenomenon – Wikipedia

Are you a health professional able to prescribe or dispense drugs? Eur J Endocrinol ; 3: Prevalence of thyroid dysfunction and effect of contrast medium on thyroid metabolism in cardiac patients undergoing coronary angiography. It is efscto after the German physician Karl Adolph von Basedow. Lancet ; In some ways the Jod-Basedow phenomenon is the opposite of the Wolff—Chaikoff effectwhich refers to the short period of thyroid-hormone suppression which happens in normal persons and in persons with thyroid disease, when comparatively large quantities of iodine or iodide are ingested.

The Wolff—Chaikoff effect has been used as a treatment principle against hyperthyroidism especially thyroid storm by infusion basevow a large amount of iodine to suppress the thyroid gland.

The Jod-Basedow effect is named for the German word for iodine”Jod” all nouns are capitalized in Germanplus the name of Karl Adolph von Basedowa German physician who first described the effect. You can change the settings or obtain more information by clicking here. Thyroid functions after contrast agent administration for coronary angiography: Iodine excess and hyperthyroidism. Print Send to a friend Export reference Mendeley Statistics. Longo, Joseph Loscalzo The Wolff—Chaikoff effect is known as an autoregulatory phenomenon that inhibits organification in the thyroid glandthe formation of thyroid hormones inside the thyroid follicle, and the release of thyroid hormones into the bloodstream.